Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects.
| Author | |
|---|---|
| Abstract |
:
The physiological challenges posed by hypobaric hypoxia warrant exploration of pharmacological entities to improve acclimatization to hypoxia. The present study investigates the preclinical efficacy of sphingosine-1-phosphate (S1P) to improve acclimatization to simulated hypobaric hypoxia. |
| Year of Publication |
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0
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| Journal |
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PloS one
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| Volume |
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9
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| Issue |
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6
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| Number of Pages |
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e98025
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| Date Published |
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2014
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| URL |
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http://dx.plos.org/10.1371/journal.pone.0098025
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| DOI |
:
10.1371/journal.pone.0098025
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| Short Title |
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PLoS One
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| Download citation |