Mcm10 proteolysis initiates before the onset of M-phase.
| Author | |
|---|---|
| Abstract |
:
Mcm10 protein is essential for initiation and elongation phases of replication. Human cells proteolyze Mcm10 during mitosis, presumably to ensure a single round of replication. It has been proposed that anaphase promoting complex ubiquitinates Mcm10 in late M and early G1 phases. |
| Year of Publication |
:
2010
|
| Journal |
:
BMC cell biology
|
| Volume |
:
11
|
| Number of Pages |
:
84
|
| Date Published |
:
2010
|
| URL |
:
https://bmccellbiol.biomedcentral.com/articles/10.1186/1471-2121-11-84
|
| DOI |
:
10.1186/1471-2121-11-84
|
| Short Title |
:
BMC Cell Biol
|
| Download citation |
